The vacationing Chipmunks and Chipettes are turning a luxury cruise liner into their personal playground, until they become 'chipwrecked' on a remote island. As the 'Munks' and Chipettes try various schemes to find their way home, they accidentally discover their new turf is not as deserted as it seems.

Struggling songwriter Dave Seville opens his home to a talented trio of chipmunks named Alvin, Simon, and Theodore. When they become overnight music sensations, a greedy record producer tries to exploit the 'boys.' Now Dave must use a little human ingenuity and a lot of 'munk mischief to get his furry family back before it's too late.