A killer blizzard has hit Buffalo, Wyoming, where Dr. Patrick Flint is trapped inside the hospital with his family, trying to save the life of a prominent citizen. An injured drifter shows up at the door, and Patrick takes him in. When the power and communications go out that night, people start dying, and the drifter is nowhere to be found. Patrick is caught between his duty to his patient, his loyalty to his family, and his fear for all their lives. With the storm still raging, will there be any survivors left in the hospital when help finally arrives?